Journal article
Erosive esophageal reflux vs. non erosive esophageal reflux: oral findings in 71 patients.
- Deppe H Department of Oral and Maxillofacial Surgery, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675, München, Germany. herbert.deppe@mkg.med.tum.de.
- Mücke T Department of Oral and Maxillofacial Surgery, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675, München, Germany. th.mucke@gmx.de.
- Wagenpfeil S Institute for Medical Biometry, Epidemiology and Medical Informatics, University of Saarland, Homburg/Saar, Germany. sw@med-imbei.uni-saarland.de.
- Kesting M Department of Oral and Maxillofacial Surgery, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675, München, Germany. kesting@mkg.med.tum.de.
- Rozej A Department of Oral and Maxillofacial Surgery, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675, München, Germany. anna.rozej@campus.lmu.de.
- Bajbouj M Department of Internal Medical Department II, Technical University of Munich, Klinikum rechts der Isar, München, Germany. monther.bajbouj@lrz.tum.de.
- Sculean A Department of Periodontology, University of Berne, Bern, Switzerland. anton.sculean@zmk.unibe.ch.
- 2015-07-26
Published in:
- BMC oral health. - 2015
Adult
Aged
Aged, 80 and over
Anti-Ulcer Agents
Dental Plaque Index
Erythema
Female
Gastric Acid
Gastroesophageal Reflux
Humans
Male
Middle Aged
Mouth Diseases
Oral Ulcer
Periodontal Attachment Loss
Periodontal Diseases
Periodontal Index
Periodontal Pocket
Periodontitis
Photography, Dental
Proton Pump Inhibitors
Stomatitis
Tongue Diseases
Young Adult
English
BACKGROUND
The purpose of this clinical study was to assess the prevalence of acidic oral mucosal lesions and periodontal conditions in patients suffering from erosive esophageal reflux disease (ERD) compared with non erosive esophageal reflux disease (NERD) patients, both treated with long term proton pump inhibitors (PPI).
METHODS
Seventy-one patients with diagnosed GERD were studied: i.e. 29 ERD and 42 NERD patients. Thorough visual examination of the oral mucosa and a periodontal evaluation was performed. The primary outcome was defined as a statistically significant difference, between the two groups, in the presence of acidic lesions of the oral mucosa and specific periodontal parameters.
RESULTS
This study failed to demonstrate statistically significant differences between ERD and NERD patients with respect to the prevalence of oral mucosal lesions. However, significantly more ERD patients suffered from severe periodontitis (CAL ≥ 5 mm) as compared to NERD patients. Accordingly, it may be assumed that PPI-use had no adverse effects on the prevalence of acidic oral mucosal lesions and on periodontal destruction.
CONCLUSIONS
Within the limitations of this study it may be concluded that ERD and NERD patients need separate evaluation with respect to periodontal destruction. Moreover, long term PPI medication had no adverse clinical impact on acidic oral mucosal lesions and periodontal destruction. Further studies are necessary to elucidate the role of reflux in the periodontal destruction of ERD individuals.
The purpose of this clinical study was to assess the prevalence of acidic oral mucosal lesions and periodontal conditions in patients suffering from erosive esophageal reflux disease (ERD) compared with non erosive esophageal reflux disease (NERD) patients, both treated with long term proton pump inhibitors (PPI).
METHODS
Seventy-one patients with diagnosed GERD were studied: i.e. 29 ERD and 42 NERD patients. Thorough visual examination of the oral mucosa and a periodontal evaluation was performed. The primary outcome was defined as a statistically significant difference, between the two groups, in the presence of acidic lesions of the oral mucosa and specific periodontal parameters.
RESULTS
This study failed to demonstrate statistically significant differences between ERD and NERD patients with respect to the prevalence of oral mucosal lesions. However, significantly more ERD patients suffered from severe periodontitis (CAL ≥ 5 mm) as compared to NERD patients. Accordingly, it may be assumed that PPI-use had no adverse effects on the prevalence of acidic oral mucosal lesions and on periodontal destruction.
CONCLUSIONS
Within the limitations of this study it may be concluded that ERD and NERD patients need separate evaluation with respect to periodontal destruction. Moreover, long term PPI medication had no adverse clinical impact on acidic oral mucosal lesions and periodontal destruction. Further studies are necessary to elucidate the role of reflux in the periodontal destruction of ERD individuals.
- Language
-
- English
- Open access status
- gold
- Identifiers
-
- DOI 10.1186/s12903-015-0069-8
- PMID 26208714
- Persistent URL
- https://sonar.ch/global/documents/177968
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